In an exclusive all girls' secondary school, they become friends. They choose the same university, and through smoke-filled nights, lectures, sexual encounters and first loves, their bond deepens: a friendship which seems like it will last for evermore.
But then, at an end-of-year party, something happens which changes everything ...
Afterwards, they drift apart. Now Stella, a lawyer in New York, lives for her work; Laura, a struggling journalist in Dublin, is still waiting for the scoop to kick-start her career; while Amanda, broken and beautiful, lives a life of slow decay in London.
Then the phone call comes which brings them back together, to the friendship they swore would last, and the night when it all went wrong.